GPCR Signaling in Cancer

by Arun K. Shukla

2020-07-25 00:36:13

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GPCR Signaling in Cancer, Volume 145,the latest release in theAdvances in Cancer Researchseries, highlights recent developments in the area of GPCRs and cancer biology. Chapters included in this volume cover several GPCRs and their downstream effecto... Read more

GPCR Signaling in Cancer, Volume 145,the latest release in theAdvances in Cancer Researchseries, highlights recent developments in the area of GPCRs and cancer biology. Chapters included in this volume cover several GPCRs and their downstream effectors as case examples to highlight their fundamental understanding and therapeutic potential. Specific chapters address the Role of GRKs and beta-arrestins in cancer, Atypical GPCRs in cancer, the Role of a chemokine receptor (CCR) 5 in cancer, Targeting G protein-coupled receptors for therapeutics in cancer, Emerging GPCR signaling pathways in cancer, and more.

G protein-coupled receptors (GPCRs) constitute a large family of cell surface receptors which are involved in nearly every cellular and physiological event. These receptors can recognize a broad array of ligands and they are targeted by nearly one third of the currently prescribed drugs including anti-cancer therapeutics.



  • Covers the latest concepts in GPCR signaling and their relevancy to cancer biology
  • Presents new indications for anti-cancer therapeutic programs
  • Includes sections on cross-talk and signaling networks of GPCRs and effectors in molecular oncology and therapeutics
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Book Details

File size9 X 6 X 0.68 in
Print pages164
PublisherAcademic Press
Publication date February 21, 2020
LanguageEnglish
ISBN9780128202319

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