Science & Math | Mathematics

Dose Finding by the Continual Reassessment Method

by Ying Kuen Cheung

2020-07-15 00:29:35

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This book presents the continual reassessment method (CRM) as a tool for dose-finding studies. With a focus on the implementation and practice of the CRM and its variations, it explains how the CRM may be calibrated and extended to suit common clinic... Read more
This book presents the continual reassessment method (CRM) as a tool for dose-finding studies. With a focus on the implementation and practice of the CRM and its variations, it explains how the CRM may be calibrated and extended to suit common clinical settings. The book includes examples of real clinical trials data to illustrate the calibration techniques and shows how R can be used to carry out the techniques. It reviews the literature, related methodology, and theoretical properties of the CRM. It also explores alternatives for situations where the CRM fails. Less

Book Details

Publication date March 29, 2011
Languageeng
ISBN9781420091526
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Ying Kuen Cheung
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